Showing posts with label epigenetic changes. Show all posts
Showing posts with label epigenetic changes. Show all posts

Tuesday, August 27, 2013

Fat as disease?

A recent article from Dr. Mercola poses a very vexed question. It’s one we might all well ask ... Cui bono? Who benefits? In categorizing obesity as a disease it opens the door for drug treatment and even, potentially, for vaccination - but as Mercola states so plainly - “obesity is no more a disease than smoking!”

The factors that have brought us to the worldwide obesity crisis are many in number, they may not yet be fully elucidated, but certainly include the following:

  • epigenetic changes (trans-generational fatties)
  • unhealthy gut microbiota courtesy of Caesarean sections
  • unhealthy gut microbiota courtesy of formula feeding
  • hormonal and neurotransmitter imbalance
  • processed food
  • refined food
  • food containing high fructose corn syrup (HFCS)
  • over supply-under nutrition
  • inappropriate advertising of unhealthy foods
  • sedentary lifestyle
  • loss of muscle mass
  • chronic toxic burden
  • unresolved stress

and on and on the list goes. The issues are many and varied and each individual will be affected by a different combination of them, so clearly the solution can’t be found in a drug or a vaccine, yet that’s the way the medical profession (in the US at least) is headed. In the same way, the mental health issues, with a similar long list of 21st century contributing factors as their root cause, are now categorised, medicalised and treated with expensive pharmaceuticals.

But back to the fat burden ... having recently seen an acquaintance who has lost 50Kg thanks to lap-banding surgery, I can tell you that nothing at all in her life has been solved. She looks terrible, feels nauseous all the time, and has not changed a single solitary one of the factors that have contributed to her lifetime of obesity and now to her long list of co-morbidities.

When will common sense prevail and true health promotion measures be applied by those who take the Hippocratic Oath?




Wednesday, March 13, 2013

Don’t wait til you’re pregnant to improve your diet ...


Pioneering studies by molecular geneticist, Robert A. Waterland shed some light on how the foods that an about-to-be or newly-pregnant mother eats in the days and weeks before and around the time of conception, may affect the way genes function in her children, and consequently her children's health. 

Waterland, funded by the U. S. Department of Agriculture, has examined subsistence farming villages in West Africa, tracking the epigenetic changes and linking them to the dramatic seasonal differences in the diets (both amount and types of foods) of women in the villages. His research not only confirms the vital importance of pre and peri-conception diet and supplementation habits, but sheds light on how the epigenetic mechanism actually works. If you’re not familiar with the term “epigenetics”, it simply means above and beyond genetics. For those who are interested in the actual mechanisms, they can impact, for example, the levels at which an everyday biochemical process, DNA methylation, occurs at regions of certain genes. DNA methylation is essential for cell development and for stabilizing cell function.

So epigenetic changes occur at the most fundamental cellular level and are exhibited across generations. While Waterland observes the negative genetic impact of dietary restriction (for example during the peak rainy season) his work provides yet more compelling incentives to get your diet into great shape before you conceive. Then back it up with robust supplementation to ensure those epigenetic effects are positive not negative ones!

       
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